Throw Momma from the Train	A clip from The Oprah Winfrey Show appeared in Throw Momma from the Train.
Mrs. Doubtfire	In the beginning of the film Mrs. Doubtfire, when Robin Williams replaced the cartoon character's voice by saying smokin's a real killer, his boss Louie said that it's a cartoon, not the Oprah Winfrey special.
Ocean's Thirteen	A clip from The Oprah Winfrey Show appeared in Ocean's Thirteen.
White Chicks	In White Chicks, one of the two cops (posing as a girl) starts calling for Oprah (as well as Dr. Phil), because he said that it was his first time experiencing how women tend to think they're fat ("it's 'Tina the talking tummy' or "Cellulite Sally").
Scary Movie 4	The final segment of Scary Movie 4 featured Craig Bierko making an appearance on Oprah, stating his falling in love with Anna Faris' character. It was a parody of Tom Cruise's infamous incident in which he proclaimed his love for Katie Holmes. Winfrey was portrayed by Debra Wilson, who also regularly impersonated Winfrey while a cast member of MADtv.
Charlie and the Chocolate Factory	A brief clip from The Oprah Winfrey Show is shown in Tim Burton's Charlie and the Chocolate Factory.